Best Vitamin B12 Supplements

(Updated August 2025)

Vitamin B12 supplements are essential for energy production, brain function, and overall health. Our experts have analyzed the top-rated, most effective options to help you make an informed choice. Find the best vitamin B12 supplement for your health needs with our comprehensive review.

Expert Reviewed

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Trusted by Thousands

Benefits of Vitamin B12

Top 10 Vitamin B12 Supplements

Our comprehensive analysis of the most effective vitamin B12 supplements available today, ranked by quality, effectiveness and customer satisfaction.

Expert Reviewed

Third-Party Tested

Trusted by Thousands

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This website serves as a free online platform designed to provide informative content and product comparison tools for its users. Please note that the site’s owner may receive compensation from the companies featured on the site, which may influence how and where these companies (and/or their products) are displayed.

Additionally, in compliance with the Operating Agreement, the following disclosure must be prominently displayed on your website: “As an Amazon Associate, I earn from qualifying purchases.” For content posted on social media, this disclaimer should be clearly linked to your account.

1

aSquared Nutrition

Vitamin B-12 5000mcg (Methylcobalamin)

9.9

5-star
(2,831 reviews)

Picked by ... people today

2

Nature Made

Vitamin B12 1000 mcg Softgels

9.5

5-star
(38,971 reviews)

Picked by ... people today

3

Thorne

Methylcobalamin (Vitamin B12)

9.4

5-star
(2,594 reviews)

Picked by ... people today

4

Garden of Life

Vitamin Code Raw B12

9.3

5-star
(1,456 reviews)

Picked by ... people today

5

aSquared Nutrition

Methyl B-12 Drops (5000mcg)

9.2

5-star
(929 reviews)

Picked by ... people today

6

Mary Ruth's

Vitamin B12 Spray

9.0

5-star
(3,247 reviews)

Picked by ... people today

OLLY Daily Energy Gummy Vitamin B12

8.8

5-star
(15,623 reviews)

Picked by ... people today

8

Klean Athlete

Klean ATHLETE B-Complex Capsules

8.6

5-star
(567 reviews)

Picked by ... people today

9

Nordic Naturals

Men's Multivitamin Gummies

8.5

5-star
(1,834 reviews)

Picked by ... people today

10

Vegetology

Vegan B12 Sustained Release

8.4

5-star
(743 reviews)

Picked by ... people today

Top Rated Vitamin B12 Supplement

aSquared Nutrition

Vitamin B-12 5000mcg (Methylcobalamin)

9.9

5-star
(2,831 reviews)

Picked by ... people today

Vitamin B12 Supplements Buyer’s Guide

It’s no secret that your body requires proper nutrition in order to function correctly, and most people simply assume this means eating a healthy diet and drinking enough water. But the reality is that diet alone isn’t always sufficient for ensuring that you’re receiving the correct nutrients and vitamins you need each day, putting you at risk of serious deficiency and on-going issues that could affect your health.

From unbeatable fatigue to a compromised immune system, there are numerous indicators that could suggest that your day-to-day meals aren’t quite meeting all of your needs, and that you may need to take additional steps to fill in potential gaps. Thankfully, the market is absolutely brimming with a never-ending selection of supplements for you to take advantage of, and one quick trip to a local pharmacy will reveal shelf after shelf of different vitamins that you can start incorporating into your routine.

Why Vitamin B12 is Essential

Vitamin B 12 is particularly crucial, especially if you’ve started to notice you’re experiencing decreased energy, brain fog, or even anemia. This essential vitamin plays vital roles in red blood cell formation, DNA synthesis, and proper neurological function. Without adequate B 12 levels, your body cannot produce healthy red blood cells, leading to megaloblastic anemia and a host of other health issues.

Forms of Vitamin B12

Methylcobalamin

The natural, bioactive form of B12 that’s easily absorbed and utilized by the body. This form is particularly effective for neurological health and doesn’t require conversion.

Cyanocobalamin

The synthetic form commonly found in supplements and fortified foods. While stable and cost-effective, it requires conversion to active forms in the body.

Who Needs B12 Supplements?

♥ Vegans and Vegetarians: Plant-based diets lack natural B12 sources
♥ Adults over 50: Decreased stomach acid production affects B12 absorption
♥ People with digestive disorders: Conditions like Crohn’s disease or celiac disease
♥ Those taking certain medications: Metformin, PPIs, and other drugs can interfere with B12 absorption

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